Open access
Sep 2026
A combined program of induced stemness and differentiation in response to IFNγ drives acute myeloid leukaemia growth
How inflammation shapes acute myeloid leukaemia (AML) has come under scrutiny, as it may explain the disease’s resistance to immunotherapy approaches. IFNγ has emerged as a key cytokine with paradoxical roles in suppressing and supporting AML growth, and the fundamental question of how leukemic stem cells (LSCs) respon...
C. Pospori, A. Donada, Helena Boutzen et al.
· bioRxiv · 0 citations