Author

T. van Eimeren

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Open access Sep 2026

Dynamic [18F]PI-2620 recording facilitates prediction of β-amyloid positivity and simultaneous staging of tau and neurodegeneration

Patients with Alzheimer’s disease (AD) and clinically overlapping neurodegenerative diseases are classified molecularly using the A/T/N classification system. Apart from fluid biomarkers and structural MRI, A/T/N assessment incorporates β-amyloid-PET (A), tau-PET (T), and [18F]FDG-PET (N). We evaluated if dynamic featu...

Johannes S. Gnörich, J. Kusche-Palenga, Agnes Kling et al. · Molecular Neurodegeneration · 0 citations

Open access Sep 2026

Resilience mechanisms in Parkinson's disease: a domain-specific conceptual framework.

While nigrostriatal dopaminergic cell loss is the pathological hallmark of Parkinson's disease, it is well-known that dopamine deficiency cannot fully explain the clinical severity or disease progression. Emerging data suggest that resilience, i.e. the brain's capacity to maintain function despite pathology, plays a ke...

M. C. Ruppert-Junck, T. van Eimeren, Kathrin Giehl et al. · Brain : a journal of neurolo... · 0 citations

Open access Sep 2026

Dopamine-Deficiency-Related Reorganization of the Somatomotor Network in Prodromal and Early Parkinson's Disease.

Dopaminergic depletion is associated with a targeted SMN reorganization, potentially maintaining network information flow despite progressive hub loss, and whether this reorganization represents compensation or a consequence of progressive pathology requires further longitudinal assessment.

Adrian L. Asendorf, Verena Dzialas, T. van Eimeren et al. · Movement Disorders · 0 citations