Open access
Jul 2026
Can we trust subthalamic local field potentials? Geometric and dynamical constraints on the interpretation of extracellular recordings
The results show that the interpretability of extracellular signals depends critically on neuronal morphology and synchronization state, and provide a mechanistic framework for the use of STN LFPs as biomarkers in adaptive deep brain stimulation for Parkinson’s disease.
F. Fattorini, T. V. Ness, L. G. Amato et al.
· bioRxiv · 0 citations