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Open access Oct 2026

Rational mRNA Structure-guided Attenuation Enables Embryo-safe in-ovo NDV Vaccination and Protection

Newcastle disease virus (NDV) continues to cause major economic losses in poultry, driving many recent virulent outbreaks. Maternally derived antibodies (MDA) can interfere with the development of active immunity following vaccination in young chicks. NDV vaccine strains that are safe for day-old chicks are not safe fo...

T. Tuller, Zohar Zafrir, Dana Goldenberg et al. · 0 citations
Open access Oct 2026

Monitoring the translation initiation process in prokaryotes via large-scale examination using optimized SSU-seq technique

Translation initiation is a critical stage of protein synthesis in prokaryotes, where ribosomes assemble on mRNA to begin decoding genetic information. The interactions between ribosomal RNA (rRNA) and mRNA significantly influence this process, with features like ribosomal binding site (RBS) affecting ribosomal dynamic...

Larissa Fine, A. Diament, R. Cohen-Kupiec et al. · 0 citations

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