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Author

T. Tuccinardi

3 papers indexed here

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Open access Oct 2026

Identification of an Unsaturated Hydroxy Fatty Acid Antitumor Oxylipin from Brown Alga Scytosiphon lomentaria: (E)-6-Hydroxyoctadec-4-enoic Acid (NP-011548)

Marine brown algae are an important source of bioactive metabolites with promising anticancer potential. Scytosiphon lomentaria has repeatedly shown selective antitumor activity, although the active metabolite associated with its lipophilic fractions had not previously been identified. Here, five solvent extracts were...

Matteo Mauceri, Abdul-salam Juhmani, R. Zangrando et al. · 0 citations
#protein folding Open access Oct 2026

Development of N -Hydroxyindole-2-Carboxamides as New Host-Targeted Broad-Spectrum Antiviral Agents Against Human Respiratory Viruses

The discovery of a novel N-hydroxyindole-2-carboxamide class of PDIA3 inhibitors, exemplified by compound AV22 (1o), which effectively inhibits PDIA3 activity and exerts broad-spectrum antiviral activity against major human respiratory viruses.

G. Bononi, G. Sibille, Erika Plicanti et al. · 0 citations
Open access Jul 2026

LogPpred: An AI-Based Predictive Model for Accurate Estimation of Molecular LogP

The development of LogPpred, an AI-based predictor of molecular lipophilicity, a robust, accurate, and transparent tool for the early assessment of molecular lipophilicity in medicinal chemistry and drug discovery is reported.

Lisa Piazza, Lara Sortino, Alessio Costa et al. · 0 citations

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