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Author

T. Toptaş

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2 papers indexed here

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Open access Sep 2026

Intensive Versus Non-Intensive Therapy in Older Patients with Acute Myeloid Leukemia: A Real-World Experience

In this real-world cohort of older patients with AML, no statistically significant differences in PFS or OS were observed between intensive and non-intensive treatment strategies, highlighting the relevance of functional status in individualized treatment selection.

Dila Elifsu Yuksekli, A. Bayar, Ceren Uzunoglu Guren et al. · 0 citations
Open access Apr 2026

RNA sequencing detects more challenging cases of somatic hypermutation in the IgHV gene in patients with chronic lymphocytic leukemia

Background/aim Chronic lymphocytic leukemia (CLL) exhibits marked biological heterogeneity, and immunoglobulin heavy chain variable (IgHV) mutation status remains a key prognostic biomarker. We evaluated patient IgHV status via RNA sequencing (RNA-seq) and examined real-life clinical outcomes in a retrospective CLL coh...

F. Arıkan, P. Ata, Şenol Demir et al. · 0 citations

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