Adolescent binge alcohol alters late-developing brain regions and increases the risk for long-term reward, cognitive, and emotional dysregulation. Adolescent intermittent ethanol (AIE) exposure in rodents produces similar behavioral alterations into adulthood, but the effects of acute high-dose ethanol on patterns of n...
Harper J. Coleman, Devon T. Applegate, Kimberly M. Papastrat et al.· Journal of Neuroscience Rese...· 0 citations
Early initiation of alcohol use is a risk factor for developing alcohol use disorder (AUD) later in life, yet the long-term neuronal consequences of adolescent drinking remain poorly understood. The central amygdala (CeA) drives the negative emotional states that promote excessive drinking, and its overactivation is a...
Paige Marsland, Peter T. Penta, T. T. Towner et al.· Neuropharmacology· 0 citations
The impacts of endocannabinoids, the neurotrophin Brain-derived Neurotrophic Factor, and cell adhesion systems in both medial and lateral compartments of the OFC are summarized to highlight other neuromodulatory factors that have received less attention but are also potent regulators of OFC-dependent decision making.
Sophie T. Yount, T. T. Towner, S. Gourley· Neurobiology of Disease· 0 citations
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