Intrathecal KFLC synthesis represents a highly sensitive CSF marker that supports early suspicion of autoimmune encephalitis and prompts antibody testing and NfL provides robust biochemical information on baseline disease severity and longitudinal changes that may aid prognostic assessment across AE subtypes.
F. Konen, E. Bucak, F. Bachhuber et al.· Neurology(R) neuroimmunology...· 0 citations
Differentiation between AD and FTD should not rely on single cognitive domains; the most clinically meaningful distinction is achieved through a multidimensional assessment integrating episodic memory, social cognition, and selected executive and behavioral measures.
Jana Marie Freitag, F. Konen, J. Heck et al.· Journal of Alzheimer's Disea...· 0 citations
The 2024 revisions of the McDonald criteria aim to facilitate an accurate and early diagnosis of MS potentially enabling earlier MS therapy initiation, however, the routine implementation requires an expansion of resources and expertise limiting the general applicability in the German healthcare system.
M. P. Wattjes, A. Bayas, Stefan Bittner et al.· Therapeutic Advances in Neur...· 0 citations
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