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T. Škovránek

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Open access Aug 2026

Physics-Informed Modeling of Biological Aging through DNA Methylation Entropy

An information-theoretic framework for DNA methylation dynamics combined with nonlinear machine learning is introduced to develop a competitive and interpretable age predictor and the Stacy Gradient Boosting Clock (Stacy-GB), which combines this GGD-based representation with a LightGBM regressor.

Hosein Nasrolahpour, Ales Jandera, T. Škovránek et al. · 0 citations

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