T. Rhee

Estimates of Anxiety Symptoms Among US Adolescents.

Importance Anxiety symptoms are common among US adolescents and associated with substantial psychiatric burden, yet contemporary nationally representative estimates of anxiety symptom severity, associated clinical conditions, and treatment utilization are lacking. Objectives To estimate the prevalence of anxiety symp...

Next-Generation Pharmacotherapies for Unipolar Mood Disorders: A Leading Article on Phase II/III Drug Development Across Diverse Mechanisms

Cognitive effects of ketamine and esketamine treatment for major depressive and bipolar disorder: a systematic review.

BACKGROUND Cognitive impairment is a core feature of major depressive disorder (MDD) and bipolar disorder (BD). Most conventional antidepressants do not have direct and clinically relevant procognitive effects. Ketamine and esketamine are effective in treating treatment-resistant depression (TRD). Herein, this systemat...

A Systematic Review of Long-term Safety Outcomes of Ketamine and Esketamine in Patients with Treatment-resistant Depression.