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T. Rajasekera

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Open access Sep 2026

Associations of endocannabinoids and related lipid mediators with depressive symptoms during perimenopause.

BACKGROUND Perimenopause is associated with increased vulnerability to depressive symptoms, partly driven by fluctuations in gonadal steroid hormones, particularly estradiol. The neurobiological mechanisms underlying this vulnerability remain unclear. Alterations in the endocannabinoid system (ECS) during perimenopause...

T. Rajasekera, S. Rahman, Doruntina Fida et al. · 0 citations

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