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T. Polte

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Open access Aug 2026

CD97/ADGRE5 attenuates the induction of adaptive type 2 immune responses in allergic asthma

Allergic asthma results from an uncontrolled type 2 immune response to inhaled allergens. Here, we investigate the function of CD97/ADGRE5, expressed in mouse and human immune and lung epithelial cells, in this disease. Female Cd97−/− mice exhibit an exacerbated asthmatic phenotype across multiple models, primarily due...

Gabriela Aust, A. Hoh, J. Alladina et al. · 0 citations

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