Background: Klotho is an anti-aging protein with demonstrated neuroprotective properties in preclinical models of Parkinson's disease (PD). However, the relationship between Klotho levels and clinical outcomes in human PD remains unclear. Objective: To examine associations between Klotho levels and cognitive/motor func...
L. Fontenele, Petrone Bandeira dos Santos, T. Paranhos et al.· ANPAbstract_CBN26· 0 citations
Findings support the potential value of EOAD-signature atrophy as an MRI-based biomarker for individualized prognostication and clinical trial stratification and support the potential value of EOAD-signature atrophy as an MRI-based biomarker for individualized prognostication and clinical trial stratification.
T. Paranhos, Yuta Katsumi, M. Brickhouse et al.· Neurology· 0 citations
This case report supports further controlled clinical trials using functional connectivity guided rTMS in PCA and supports the hypothesis that intermittent theta burst, a form of rTMS, can modulate functional networks and improve associative memory in a patient with PCA presenting with memory impairments.
T. Paranhos, Anna Du, Ryan Eckbo et al.· International Review of Psyc...· 1 citation
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