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Open access Oct 2026

Developmental prefrontal myelination shapes inhibitory interneuron function and adult social behavior

Early-life adversity and abnormal myelination are implicated in psychiatric disorders, but how developmental myelination influences adult social cognition remains unclear. Here, we tested whether disrupting developmental myelination in the medial prefrontal cortex (mPFC) impairs adult social behavior. Using complementa...

Takahira Yamauchi, Kohei Kamikawa, Kazuhiko Yamamuro et al. · 0 citations
Open access Sep 2026

765. Phosphorylation Mapping Reveals New Brain Networks Linked by Antipsychotic Drugs

Abstract Background While the target molecules for neuropsychiatric drugs have been identified, their specific mechanisms of action within brain regions and cells are still unknown. To enhance mental health treatments, it is crucial to conduct a comprehensive analysis of the effects of current therapeutic agents on dif...

P. K. Sarker, D. Tsuboi, Y. Funahashi et al. · 0 citations

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