T. N. de Villavicencio Diaz

B-149 From Polyclonal to Recombinant: A Proteomics Workflow for Anti-Idiotype Antibody Development

Anti-idiotype antibodies are essential tools for therapeutic drug monitoring of biologic therapies in cancer, inflammatory bowel disease, and rheumatoid arthritis. While several platforms exist for their development, including B-cell immortalization and phage display, we employ a proteomics-based mass spectrometr...