Molecular Dynamics Study of FRET Orientation Factors to Infer the Structural Deformations in Damaged DNA
In Förster resonance energy transfer (FRET) experiments for probing DNA structural deformations, the orientation factor κ2 is critical for accurate distance estimation. Although κ2 depends on the molecular behavior of fluorescent dyes, its quantitative variation remains insufficiently understood. To elucidate this e...