T. Maruyama

Three current approaches to preclinical oral squamous cell carcinoma research: a practical, stepwise framework integrating cell lines, organoids, and animal models.

Oral squamous cell carcinoma (OSCC) continues to be associated with a poor prognosis despite recent advances in surgical and adjuvant treatment. Although a variety of experimental models are available, no widely accepted or practical framework has combined cell lines, patient-derived organoids, and in vivo transplantat...