Author

Tony Kam-Thong

2 papers indexed here

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Open access Sep 2026

Physiological variability in key Alzheimer's biomarkers in amyloid-positive clinical trial cohorts and the mechanistic basis of biomarker ratios

Background: Protein biomarkers in cerebrospinal fluid (CSF) and plasma have established themselves as essential tools for the diagnosis of neurological disorders and for disease monitoring, thanks to their accuracy and clinical validity. Outside their original intended context of use, protein biomarkers are increasingl...

E. Tasiudi, D. J. Hawellek, E. Aponte et al. · medRxiv · 0 citations

Open access Jul 2026

Clinically altered brain activity may not look like aged brain activity: Implications for brain‐age modeling and biomarker strategies

Abstract INTRODUCTION Brain‐age gap (BAG), the difference between predicted age and chronological age, is studied as a biomarker for the natural progression of neurodegeneration. The BAG captures brain atrophy as measured with structural magnetic resonance imaging (MRI). Electroencephalography (EEG) has also been explo...

L. Gemein, S. Gaubert, Claire Paquet et al. · Alzheimer's & Dementia · 0 citations