Author

T. Jepps

2 papers indexed here

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Oct 2026

Effect of Colchicine on Arterial Stiffness in Patients With Hypertension: The COlchicine HypERtENsion Trial (COHERENT).

AIM This trial investigated whether colchicine, an anti-inflammatory treatment, affects cardiovascular structure and function, assessed by arterial stiffness, blood pressure and biochemistry, compared with placebo. METHODS COHERENT was a randomized, double-blind, placebo-controlled trial of the effects of colchicine...

A. Langhoff, N. Johansen, K. Bartholdy et al. · European Journal of Preventi... · 0 citations

Open access Oct 2026

Effects of colchicine on cardiac structure and function in patients with hypertension: a prespecified secondary analysis of the COlchicine HypERtENsion Trial (COHERENT)

Hypertension is a common and important risk factor for cardiovascular (CV) disease. The immune system and inflammatory response contribute to the pathology of hypertension. Colchicine has shown promise in delaying the progression of manifest atherosclerotic disease. However, the effects of colchicine on cardiac s...

A. Langhoff, N. Johansen, K. Bartholdy et al. · European Heart Journal · 0 citations