Synthetically accessible naphthalene-based rigid-core electrolytes as membrane-active antibacterial agents against drug-resistant pathogens.
A naphthalene-based rigid-core electrolyte platform that removes the phenylene-vinylene linker while retaining potent antibacterial activity is reported, which identifies compact scaffold rigidity, linker length, and cation identity as important design variables for this RCE series and support further pharmacokinetic,...