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T. Hohman

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Open access Jul 2026

Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.

Higher plasma p-tau217 levels were consistently associated with increased risk of clinical progression and accelerated cognitive decline, and support the potential of p-tau217 for prognostic model development, with direct implications for future trial design.

R. Buckley, D. Townsend, C. Birkenbihl et al. · 3 citations
Open access Jul 2026

A comparative evaluation of multiple enlarged perivascular space segmentation tools.

DORES provides a multimodal nnU-Net-based pipeline for ePVS segmentation in older adults and demonstrates robust within-cohort performance and reasonable external validity, though scanner-related effects limit application across sites.

James D. LeFevre, W. Robb, Dan-Dan Liu et al. · 0 citations
Open access Jul 2026

Is correction for gradient nonlinearity necessary in a brain diffusion tensor MRI clinical study?

A simple power analysis indicates that these subtle effects of gradient nonlinearity correction can become statistically detectable in larger multi-site studies exceeding ~1000 subjects, suggesting that GNL should be considered and, where possible, corrected or at least quantified in such settings.

Praitayini Kanakaraj, Tianyuan Yao, Zhiyuan Li et al. · 0 citations

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