Author

T. Harada

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Open access Sep 2026

Sotatercept Improves Right Heart Mechanics Despite Reduced Myocardial Contractility in Pulmonary Arterial Hypertension - A Prospective Exercise Hemodynamic Study

Background: The right ventricular (RV) response to pressure overload is a crucial determinant of outcomes in pulmonary arterial hypertension(PAH). Sotatercept improves clinical outcomes, but its effects on the RV have been inconsistent. We sought to evaluate the effects of sotatercept on load-independent measures of RV...

Y. Reddy, S. Kazui, W. Miranda et al. · Circulation · 0 citations

Sep 2026

Exercise stress echocardiography for diagnosis of heart failure with preserved ejection fraction: a multicentre study.

Addition of LA strain imaging with optimized rule-in or rule-out values improves diagnostic triage by expanding non-invasive rule-in/rule-out classifications while identifying patients who still require invasive testing in the evaluation of HFpEF.

T. Harada, Yogesh N. V. Reddy, H. Sorimachi et al. · European Heart Journal · 0 citations