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Author

T. Ghazanfari

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2 papers indexed here

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Oct 2026

Evaluation of mRNA expression and DNA methylation status of immune checkpoints in the peripheral blood of COVID-19 patients.

BACKGROUND COVID-19 immunopathology involves dysregulated immune responses, partly mediated by inhibitory immune checkpoints (ICs). Epigenetic mechanisms, particularly DNA methylation by DNA methyltransferases (DNMTs), regulate gene expression. However, the interplay between IC transcription, promoter methylation, and...

E. Mirsharif, A. Rostamian, M. Salehi et al. · 0 citations
Open access Oct 2026

An integrated immunoinformatics and experimental pipeline identifies an LCL-scaffolded OmpA loop 3 construct as a protective vaccine candidate against Acinetobacter baumannii.

Acinetobacter baumannii has emerged as a critical nosocomial pathogen due to its extensive antimicrobial resistance and limited treatment options, highlighting the urgent need for effective vaccines. In this study, we developed and evaluated a rationally engineered epitope-based vaccine targeting extracellular loop 3 o...

Seyyedeh Reyhaneh Banisaeed, I. Rasooli, T. Ghazanfari et al. · 0 citations

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