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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

T. Furuyashiki

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Open access Sep 2026

Synaptic Mitochondrial Oxidative Stress Contributes to Individual Variability in Age‐Related Cognitive Inflexibility in Mice

Aging is associated with impairments in cognitive flexibility, a key executive function supported by the medial prefrontal cortex (mPFC), yet the biological mechanisms underlying individual variability in age‐related decline remain poorly understood. Here we investigated behavioral, ultrastructural, and proteomic corre...

Rui Yamada, H. Nagai, C. Numa et al. · 0 citations
Open access Sep 2026

499. Chronic stress impairs synaptic central metabolism in the prefrontal cortex, driving depression-related behaviors in mice

It is demonstrated that chronic stress disrupts central energy metabolism at prefrontal cortical synapses, driving to synaptic pathology and behavioral vulnerability and highlighting synaptic metabolic pathways as promising pharmacological targets for the treatment of stress-related psychiatric disorders.

H. Nagai, K. Ota, C. Numa et al. · 0 citations

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