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Open access Oct 2026

Impact of in-hospital intensification of heart failure medical treatment on clinical outcomes in dialysis-dependent patients with worsening heart failure

Patients undergoing maintenance dialysis represent a high-risk population for cardiovascular events. Major randomised trials evaluating guideline-directed medical therapy (GDMT) components for heart failure (HF), such as renin-angiotensin system inhibitors (RASis), angiotensin receptor neprilysin inhibitor (ARNI)...

K. Ikuta, T. Hashimoto, S. Matsushima et al. · 0 citations
Open access Oct 2026

In-hospital treatment intensification and outcomes in patients hospitalised for worsening heart failure in the current era of guideline-directed medical treatment

The real-world impact of intensifying contemporary guideline-directed medical therapy (GDMT) during hospitalisation on long-term outcomes in patients with heart failure (HF) remains uncertain. This study aimed to evaluate the association between in-hospital GDMT intensification and long-term outcomes in pa...

T. Hashimoto, R. Matsukawa, S. Matsushima et al. · 0 citations

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