T. D. de Souza

Investigation of naturally derived compounds with antibiofilm activity against Candida albicans.

Novel compounds from natural sources that can inhibit and eradicate Candida albicans biofilms were investigated. Four compounds (26.7%) inhibited 50% or more biofilm formation at a single dose out of fifteen compounds evaluated. Among them, three terpenoid derivatives (2, 4 and 6) did not show antifungal activity at th...