Bone FGF23 expression and renal regulatory responses to excess phosphate consumption by juvenile swine
Roles of FGF23 in P homeostasis in a large animal, healthy swine model were validated, with HP consumption stimulated bone FGF23 expression and renal adaptive responses in healthy pigs, consistent with roles of FGF23-mediated phosphaturia and regulation of vitamin D metabolism for maintenance of P homeostasis.
M. Grez-Capdeville, Brittney P. Kokinos, L. Amundson et al.
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