T. Cortes

Mycobacterium tuberculosis gene expression dynamics in host environments with single-cell resolution.

Visualizing when and where Mycobacterium tuberculosis (Mtb) genes are expressed in the host cell is crucial to understand tuberculosis heterogeneity. However, imaging approaches for studying spatiotemporal gene expression in Mtb remain limited. Here, we developed a dual-fluorophore Mtb reporter system that enables high...