Biological aging occurs heterogeneously across individuals and organs. However, current measures of biological age incompletely capture organ-specific differences in health and disease risk. Because chest CT visualizes multiple thoracic organs, it offers an opportunity to quantify structural aging across organ systems....
J. Sato, M. Salehjahromi, A. Zafar et al.· medRxiv· 0 citations
Background Lung cancer remains the leading cause of cancer-related deaths in the United States with over 124,000 estimated deaths for 2026. Previous studies have found that tumor-adjacent lung tissues may provide additional insight into the immune microenvironment of early-stage NSCLC. Methods Multiplex immunofluoresce...
Isabella Polic, Claudio J. Arrechedera, Jared K. Slone et al.· bioRxiv· 0 citations
The treatment of early-stage non-small-cell lung cancer (NSCLC) has evolved substantially in recent years. For decades, curative-intent surgery followed by platinum-based chemotherapy remained the standard of care (SOC), despite delivering only modest gains in long-term survival. Current evidence from randomised trials...
Jordi Remon, T. Cascone, S. P. Saw et al.· The Lancet Respiratory Medic...· 2 citations
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