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Author

T. C. Friedrich

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Open access Sep 2026

Evaluation of a Zika virus-like particle-based vaccine in a highly penetrant non-human primate model of congenital infection

A highly pathogenic nonhuman primate pregnancy model is evaluated for its ability to assess vaccine-mediated protection using a Zika virus-like particle (VLP) vaccine as a test platform and results support a high risk of early pregnancy loss following African-lineage ZIKV-DAK 41524 infection in RM.

Hannah K. Jaeger, Jessica L. Smith, C. Labriola et al. · 0 citations
Open access Aug 2026

Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection

It is suggested that KIR3DL01+ NK cells contribute to the inhibition of SIV replication during chronic infection, and the feasibility of AAV-vectored antibody delivery for long-term, perhaps indefinite depletion of a lymphocyte subset in a nonhuman primate model is demonstrated.

Kjell Sandstrom, Grace N. Hagedorn, Sean C Robinson et al. · 0 citations

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