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Open access Aug 2026

Comparison of quantitative digital and semiquantitative assessments of tau pathology in relation to regional in vivo tau PET.

Quantitative digital image analysis has emerged as a powerful tool for assessing neuropathological burden. Although previous studies have compared quantitative digital and semiquantitative pathology measures, their respective relationships with regionally corresponding in vivo tau PET measures remain poorly characteriz...

Cécilia Tremblay, Tove Freiburghaus, Daria Pawlik et al. · 0 citations
Open access Aug 2026

Increased Binding of [18F]Nifene, a PET Imaging Probe for α4β2* Nicotinic Acetylcholinergic Receptors in Hippocampus–Subiculum of Postmortem Human Parkinson's Disease Brain

Non‐motor symptoms in Parkinson's disease (PD) may be influenced by the α4β2* subtype of nicotinic acetylcholine receptors (nAChRs) present in the hippocampus (HP) and subiculum (SUB). To continue efforts in positron emission tomography (PET) diagnostics for PD, autoradiographic [18F]nifene binding to α4β2* nAChR was q...

J. Mukherjee, Fariha Karim, Allyson Ngo et al. · 0 citations
Open access Jul 2026

Greater burden of Alzheimer's Co-pathology in women with Parkinson's disease dementia

It is found that women with Parkinson's disease Dementia are more vulnerable to developing Alzheimer's-like brain changes than men with Parkinson's disease Dementia and the need for sex-informed approaches to reseach in mixed neurodegenerative disease is supported.

Nathaniel Dunckley, Erika Driver-Dunckley, Nan Zhang et al. · 0 citations

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