An open multimodal spatial resource integrating same-tissue transcriptomics, proteomics, and histology
A workflow for sequential 10x Genomics Xenium spatial transcriptomics, COMET cyclic immunofluorescence, and haematoxylin and eosin histological staining on the same formalin-fixed paraffin-embedded tissue section is presented, illustrating the widespread applicability of the workflow beyond a single tissue type.