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T. Alramadneh

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Review Open access Oct 2026

The Microbiome in Glioblastoma: Mechanisms, Tumor–Immune Interactions, and Translational Perspectives

ABSTRACT Despite multimodal treatment, glioblastoma (GBM) remains difficult to control because of diffuse invasion, tumor heterogeneity, immune dysfunction, and frequent recurrence. Increasing attention has focused on whether intestinal microbial communities and their products can modify systemic and central nervous sy...

T. AlRamadneh, R. Jyothi S., Priya Priyadarshini-Nayak et al. · 0 citations
Review Open access Sep 2026

Recent Advances in MXene Quantum Dots for Cancer Theranostics and Immunomodulation: Design Principles, Biological Interfaces, and Translational Perspectives

Cancer remains a leading cause of morbidity and mortality worldwide, demanding innovative strategies for diagnosis, therapy, and immune modulation. Advances in nanomedicine have positioned MXene quantum dots (MQDs) as promising multifunctional platforms for cancer theranostics due to their tunable physicochemical pro...

T. AlRamadneh, J. Rizaev, Jakhongir Norqulov et al. · 0 citations
Review Open access Aug 2026

Photoluminescence Mechanisms and Optical Sensing Applications of MXene Quantum Dots for Pesticide Detection in Vegetable Matrices

The widespread occurrence of pesticide residues and inorganic contaminants in vegetables requires rapid, sensitive, and reliable analytical approaches for food safety monitoring. MXene quantum dots (MQDs) have attracted significant attention as advanced luminescent nanomaterials due to their tunable photoluminescence,...

T. Alramadneh, Flah Shryf Abdul, Amaal Mohammed Ali et al. · 0 citations
Review Aug 2026

Gasdermin-mediated pyroptosis as a prognostic biomarker and therapeutic target in hepatocellular carcinoma.

Examination of molecular circuitry linking pyroptosis with inflammasomes, metabolic stress, mitochondrial dysfunction, hypoxia, and epigenetic regulation in HCC suggests regulated pyroptosis may represent a promising immunomodulatory framework for improving precision therapy in HCC.

T. Alramadneh, Inoyatillo Kholmurodov, Naina Boboyeva et al. · 0 citations
Review Open access Aug 2026

Exosomal Non-Coding RNAs: Emerging regulators of the tumor microenvironment in gastrointestinal and hepatobiliary cancers.

Overall, EV-ncRNAs represent promising mechanistic biomarkers and therapeutic targets, but rigorous source-specific validation and standardized analytical workflows are required before clinical implementation.

T. AlRamadneh, Waleed K. Abdulsahib, Sanan Thaer Abdalwahab et al. · 0 citations
Review Sep 2026

From beta-cell stress to tertiary lymphoid structure formation: a stage-dependent framework for interpreting type 1 diabetes progression.

A stage-dependent conceptual framework linking beta-cell stress, innate immune activation, and TLS-mediated stabilization of chronic inflammation is presented, providing a rationale for the limited durability of current immune-targeted therapies and identifying experimentally testable hypotheses.

T. Alramadneh, Aziz Kubaev, Shakir Mahmood Saeed et al. · 0 citations
Review Jul 2026

EXPRESS: Circular RNAs as Next Generation Biomarkers for Minimal Residual Disease: Mechanistic Insights and Clinical Translation.

This review integrates current knowledge of circRNA biogenesis and molecular function, surveys cancer-type-specific circRNA expression signatures, and evaluates evidence for their utility in MRD monitoring across hematologic and solid malignancies, and proposes multilayered diagnostic frameworks combining circRNA profi...

T. Alramadneh, Hussein Salim Abed, Sarah Qutayba Badraldin Qutayba Badraldin et al. · 0 citations

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