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Sylwia Michlewska

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Open access Aug 2026

Txn-Txnrd1 system supports redox rewiring during polyaneuploid transition and protects giant cancer cells at new redox homeostasis

Polyaneuploid giant cells (PGCC), which occur more frequently in TP53-mutant tumors, are recognized as a driver of tumor recurrence and therapy resistance, but the mechanisms supporting their survival remain largely unknown. Our results indicate that polyaneuploid transition and subsequent PGCC maturation in drug-resis...

Kinga Kołacz-Milewska, K. Gronkowska, Sylwia Michlewska et al. · 0 citations
Open access Aug 2026

Cleavable Carbosilane Dendrimers Modulate the Thermodynamical Properties of DMPC/DPPG Lipid Membrane and Conformation of Human Serum Albumin.

Study of cationic carbosilane dendrimers interact with both DMPC/DPPG lipid bilayers and HSA in a manner that is generation-dependent and concentration-dependent, suggesting that their generation and charge density are key determinants of their behavior toward biological membranes and plasma proteins.

Paulina Rycharska, Sylwia Michlewska, Adam Buczkowski et al. · 0 citations

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