Open access
Sep 2026
Cell cycle dependent regulation of mRNA export in response to replication stress
A physical checkpoint at nuclear speckles is uncovered that regulates mRNA export during DNA replication in S-phase of the cell cycle and serves to protect the cell from major sources of genome instability by ensuring that R-loop associated mature mRNA is not exported to the cytoplasm.
Tobias D. Williams, Kirstyn T. Carey, W. Hamilton et al.
· bioRxiv · 0 citations