Preprint
Aug 2026
Simulating is not always understanding: When model complexity obscures biology
It is argued that the field needs to reconsider the goal of complex models, and move away from trying to include as many parameters as possible and instead aim for systematic comparisons with simpler representations, dynamical analysis, and explicit model hierarchies that trace how cellular behavior emerges from its pa...
L. Gelens, Alejandro Fábregas-Tejeda, Grant Ramsey et al.
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