Open access
Aug 2026
A general strategy towards multicolour fluorogenic peptides for wash-free bioassays.
Peptide-based fluorescent probes are valuable tools for live-cell imaging, but conventional labelling approaches often require washing or long incubation, limiting their signal-to-noise ratios. Fluorogenic amino acids (FgAAs) can overcome these limitations, yet their rational design remains challenging owing to the lac...
M. Wong, Lorena Mendive-Tapia, Utsa Karmakar et al.
· Nature Chemistry · 0 citations