Virus-like particle display of the SARS-CoV-2 receptor-binding domain using a modular tag/catcher system enhances immunogenicity of a DNA vaccine in mice.
The COVID-19 pandemic highlighted the critical need for adaptable, rapid-response vaccine platforms. While mRNA vaccines enabled fast and scalable development, their stringent cold-chain requirements limited global accessibility. DNA vaccines offer a similarly fast and flexible vaccine design, but require far less comp...