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Suzin Tatonyan

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Open access Sep 2026

Mitochondrial Damage in Hemoglobinopathies: The Role of Cell-Free mtDNA as a Potential Biomarker

Background/Objectives: In hemoglobinopathies such as β-thalassemia and sickle cell disease (SCD), mitochondrial dysfunction has been implicated in chronic oxidative stress and tissue damage. Circulating cell-free mitochondrial DNA (cf-mtDNA) may reflect mitochondrial injury and serve as a biomarker of disease severity...

S. T. Neijmann, A. Gedikbaşı, F. Tuncer et al. · 0 citations

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