Suzanne A. Al-Bustan

Association of APOC2 upstream variant rs10425530 with BMI predicted to overlap with NR2C2, GCM2 and NR2C1 binding sites.

BACKGROUND Lipid metabolism involves multiple genes that contribute to various diseases including metabolic disorders. Although extensive research has focused on identifying large-effect variants in coding regions, few studies have examined the effects of variations in regulatory and non-coding regions. Apolipoprotein...