Open access
2026
Development of diclofenac and metronidazole thermo-responsive mucoadhesive in situ gel for periodontal drug delivery
Periodontitis is a chronic inflammatory disease driven by anaerobic bacterial biofilms within periodontal pockets. Conventional oral dosage forms exhibit limitations in pocket retention and sustained drug exposure, necessitating more effective local delivery strategies. This study aimed to develop and optimize a thermo...
Yuwakorn Siripithaya, Kittiphon Juntaraarpa, Jaturaphat Anugul et al.
· Pharmaceutical Sciences Asia · 0 citations