Altered Excitation–Inhibition Balance and mGluR1/5-Driven Plasticity in the Motor Cortical Surface in a Rat Model of Parkinson’s Disease
Dopaminergic depletion appears to enhance network excitation and disrupt mGluR1/5-mediated control of M1 surface circuitry in hemi-parkinsonian rats, identifying altered cortical surface mGluR-dependent plasticity in the hemi-parkinsonian model.