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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Sunbok Jang

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Review Open access Sep 2026

Synthetic lethality and context-selective DNA-damage response dependencies: from genetic vulnerability to pharmacological translation.

Synthetic lethality has established DNA-damage response (DDR) dependencies as a major strategy for precision cancer therapy, exemplified by targeting BRCA1/2 and poly(ADP-ribose) polymerase (PARP). However, genetic dependency alone does not ensure pharmacological tractability or clinical utility. Emerging targets, incl...

Nayoon Jo, Su-Jin Kang, Jeongeun Kim et al. · 0 citations
Review Open access Sep 2026

PARylation at the Genome–Proteome Interface: Regulation of DNA Repair Protein Dynamics

Poly(ADP-ribosyl)ation (PARylation) is a rapid, reversible DNA damage response that promotes chromatin remodeling and the recruitment of repair factors. Genome maintenance also involves regulating the assembly, chromatin residence, exchange, and disengagement of repair proteins after lesion processing. This review exam...

Su-Jin Kang, Jiwon Eom, Yu-Bin Ko et al. · 0 citations

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