Review
Open access
Sep 2026
Stemness plasticity in hepatocellular carcinoma: spatial niches and therapeutic implications
Current evidence linking stemness plasticity to spatial niche regulation and treatment failure in HCC is synthesized, and a therapeutic framework that integrates targeting of intracellular regulatory programs with disruption of microenvironmental support systems is outlined.
H. Ahn, Sujin Kim, H. Cho
· Journal of Liver Cancer · 0 citations