BACKGROUND
Anthracycline-free TCHP and anthracycline-based AC-THP are both used as neoadjuvant dual anti-HER2 regimens for HER2-positive breast cancer, but direct comparisons accounting for HER2 immunohistochemistry (IHC) intensity are lacking. Because IHC 3+ tumors respond substantially better to dual blockade, any be...
B. Sharaf, F. Tamimi, Mohammad Alzoubi et al.· Cancer Treatment and Researc...· 0 citations
In this real-world Middle Eastern cohort, pembrolizumab-based chemoimmunotherapy achieved pCR rates consistent with pivotal trial data, and Grade 3 histology, pathogenic germline mutation, and age younger than 40 years were independently associated with pCR.
B. Sharaf, T. Al-Batsh, Suhaib Khater et al.· Breast Cancer· 0 citations
Background: Colon cancer is the fourth most commonly diagnosed cancer worldwide, with elderly individuals accounting for nearly one-third of new cases. While adjuvant chemotherapy has been associated with improved survival outcomes; its effectiveness in elderly patients remains unclear. This retrospective study was con...
Yacob Saleh, Suhaib Khater, T. Alawabdeh et al.· Jordan Medical Journal· 0 citations
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