Astrocytes exhibit pronounced, context-dependent plasticity following central nervous system (CNS) injury; however, their capacity for fate remodeling remains constrained by chromatin architecture, lineage-stabilizing signaling networks, inflammatory and metabolic states, and disease context. Canonical Wnt/β-catenin si...
Sudichhya Tamrakar, Laurence S. Pe, Jiraporn Panmanee et al.· Biomedicine & pharmacotherap...· 0 citations
Parkinson’s disease (PD) is a neurodegenerative disorder associated with dopaminergic neuronal loss, mitochondrial dysfunction, and redox imbalance. Huperzine B (HupB), an alkaloid derived from Huperzia species, has demonstrated antioxidant and acetylcholinesterase‐inhibitory activity; however, its effects in toxin‐ind...
Kittikun Viwatpinyo, Poommaree Namchaiw, Pipob Suwanchaikasem et al.· Advances in pharmacological...· 0 citations
A significant and increasing burden of dengue infection in the Kathmandu Valley between 2019 and 2023 is revealed, highlighting an urgent need for immediate public health interventions to mitigate dengue's rise in Nepal's higher-altitude regions.
A. Shrestha, Melina Thapa, S. Shrestha et al.· medRxiv· 0 citations
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