NECTIN-4 orchestrates macrophage-mediated tumor plasticity in oral squamous cell carcinoma.
Tumor associated macrophages (TAM) are key regulator of the tumor microenvironment (TME), however, the upstream factors that contribute to the polarization and functional reprogramming in oral squamous cell carcinoma (OSCC) remain largely unclear. This study evaluates the role of Nectin-4 in modulating tumor-immune int...