Author

Su-Ming Zhou

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Jul 2026

11β-HSD1 may Aggravate Sepsis-associated Endothelial Dysfunction by Activating the NF-κB/MAPK Pathway and NLRP3 Inflammasome.

11β-HSD1 may exacerbate sepsis-associated endothelial dysfunction by promoting NF-κB/MAPK signaling and NLRP3 inflammasome activation and targeting this axis represents a potential therapeutic approach for sepsis-related endothelial injury, though further validation is warranted.

Dan Wu, Dong-Mei Zhu, Haidong Qin et al. · Current Medicinal Chemistry · 0 citations