Author

S. Yu

3 papers indexed here

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Open access Sep 2026

PNPLA3 Is Associated With Hepatocellular Carcinoma, While a Five-Variant Polygenic Risk Score Shows Limited Discrimination in Korean Patients With MASLD.

BACKGROUND/AIMS Genetic variants in PNPLA3, TM6SF2, MBOAT7, GCKR, and HSD17B13 have been associated with MASLD progression and hepatocellular carcinoma (HCC). We evaluated their associations with prevalent HCC and the performance of a five-variant polygenic risk score (PRS-5) in Korean patients with MASLD. METHODS A...

Jaejun Lee, J. Cha, Hee Sun Cho et al. · Journal of Gastroenterology... · 0 citations

Review Open access Sep 2026

Toward a future role for liver biopsy in HCC: literature evidence and survey-based perspectives from Korean experts.

The role of liver biopsy in hepatocellular carcinoma (HCC) is being re-evaluated in the era of precision oncology and biomarker-driven systemic therapy. Although histopathological examination remains the diagnostic gold standard, HCC is unique among solid tumors in that accurate non-invasive imaging criteria allow diag...

Hae Lim Lee, Su-Jong Yu, Sung-Hak Lee et al. · Journal of Liver Cancer · 0 citations

Aug 2026

Liver cirrhosis is associated with altered glucocorticoid metabolism related to disease severity.

BACKGROUND Liver cirrhosis (LC) is frequently complicated by adrenal dysfunction; however, whether cirrhosis drives the coordinated, pathway-specific reprogramming of cortisol metabolism remains unclear. OBJECTIVES We aimed to characterize axis-specific alterations in cortisol metabolism in patients with LC, those wi...

Soyeon Park, Min Jeong Park, Hyehwan Yang et al. · Journal of Internal Medicine · 0 citations