Review
Open access
Oct 2026
The Role of METTL3-Mediated m6A Methylation in Hepatocellular Carcinoma Progression and Treatment
The current understanding of METTL3 biology in HCC is summarized, focusing on its structure, assembly within the MTC, regulation of coding and non-coding RNAs, and its roles in driving key oncogenic signaling cascades, such as JAK/STAT3, PI3K/AKT/mTOR, Wnt/β-catenin, Hippo/YAP, Notch, Hedgehog, and epithelial–mesenchym...
Bala Gamage Nalaka Hasith Maduranga, H. Yang, Su-In Lee et al.
· Epigenomes · 0 citations